Resverlogix Corp.

News Releases

Sign up for news alerts

PDF Version

Resverlogix Files 2017 Year-End Disclosure Documents and Announces Plans to Host a Symposium at the European Society of Cardiology Congress 2017

CALGARY, July 25, 2017 /CNW/ - Resverlogix Corp. ("Resverlogix" or the "Company") (TSX:RVX) announced today that it filed its audited Consolidated Financial Statements for the year ended April 30, 2017 and related Management's Discussion and Analysis with Canadian securities regulatory authorities. The Company has also filed its Annual Information Form for the year ended April 30, 2017. Copies of these documents may be obtained online at www.sedar.com, or the Company's website, www.resverlogix.com, or by emailing ir@resverlogix.com. An additional corporate financial update will take place prior to August 28th, 2017.

Resverlogix to Host Symposium at the European Society of Cardiology Congress 2017

The Company also announced today that on Saturday, August 26, 2017, at the European Society of Cardiology (ESC) Congress in Barcelona, Spain, it will host a symposium titled: "Managing Diabetes & CVD: Is epigenetics a new way forward?"

The agenda and speakers are as follows:

Introduction
Lina Badimon, MD – Barcelona, Spain

Managing high risk diabetes patients with cardiovascular disease: What works, and what else can we do? - Kausik Ray, MD - Imperial College London, United Kingdom

Promise of epigenetic modulation as a target in atherosclerotic patients
- Erik Stroes, MD - Academic Medical Centre, Amsterdam, Netherlands

Insights from the first trials in epigenetics in human: What is the way forward?
- Stephen Nicholls, MD - Adelaide, Australia

Presentations will be made available at: www.pace-cme.org.

Mr. Donald McCaffrey, President and CEO commented, "The presentations at the ESC Congress symposium will highlight apabetalone and its opportunity as a novel approach to the treatment of high-risk cardiovascular disease in patients with diabetes. Data to be presented demonstrates the important role for epigenetics in the underlying pathology of these diseases." Mr. McCaffrey added, "Importantly, we remain encouraged by the recent data safety monitoring board review and recommendation to once again continue with the Phase 3 BETonMACE trial as planned. The trial has already enrolled over 70 percent of the planned 2,400 patients and remains on track with internal projections."

Resverlogix will also present two posters at the congress titled:

i)

"Lowering the neutrophil to lymphocyte ratio by the BET inhibitor, apabetalone: potential implications for cardiovascular events in high risk patients"




Poster Presentation Details:




Date: Sunday, August 27, 2017


Time:   9:30am – 10:45am CET


Session number: 302


Session title: Poster Session 2



ii)

"Apabetalone (RVX-208) impacts key biomarkers and pathways associated with cardiovascular disease in patients with severe renal impairment"




Poster Presentation Details:




Date: Tuesday, August 29, 2017


Time: 3:30pm – 4:30pm CET


Session number: 307


Session title: Poster Session 7

The posters will be made available HERE on the Company's website at the time of their respective presentation dates and times at the congress.

About Resverlogix

Resverlogix is developing apabetalone (RVX-208), a first-in-class, small molecule that is a selective BET (bromodomain and extra-terminal) inhibitor. BET bromodomain inhibition is an epigenetic mechanism that can regulate disease-causing genes. Apabetalone is the first and only BET inhibitor selective for the second bromodomain (BD2) within the BET protein called BRD4. This selective inhibition of apabetalone on BD2 produces a specific set of biological effects with potentially important benefits for patients with high-risk cardiovascular disease (CVD), diabetes mellitus (DM), chronic kidney disease, end-stage renal disease treated with hemodialysis, neurodegenerative disease, Fabry disease, peripheral artery disease and other orphan diseases, while maintaining a well described safety profile. Apabetalone is the only selective BET bromodomain inhibitor in human clinical trials. Apabetalone is currently being studied in a Phase 3 trial, BETonMACE, in high-risk CVD patients with type 2 DM and low high-density lipoprotein (HDL), and is expected to be initiated in a Phase 2a kidney dialysis trial designed to evaluate biomarker changes and safety parameters in up to 30 patients with end-stage renal disease treated with hemodialysis.

Resverlogix common shares trade on the Toronto Stock Exchange (TSX:RVX).

Follow us on Twitter: @Resverlogix_RVX (https://twitter.com/resverlogix_rvx), or on our blog at http://www.resverlogix.com/blog

For further information please contact:

Investor Relations
Email: ir@resverlogix.com
Phone: 403-254-9252
Or visit our website: www.resverlogix.com

This news release may contain certain forward-looking information as defined under applicable Canadian securities legislation, that are not based on historical fact, including without limitation statements containing the words "believes", "anticipates", "plans", "intends", "will", "should", "expects", "continue", "estimate", "forecasts" and other similar expressions. In particular, this news release includes forward looking information relating to the potential role of apabetalone in the treatment of CVD, DM, chronic kidney disease, end-stage renal disease treated with hemodialysis, neurodegenerative disease, Fabry disease, peripheral artery disease and other orphan diseases. Our actual results, events or developments could be materially different from those expressed or implied by these forward-looking statements. We can give no assurance that any of the events or expectations will occur or be realized. By their nature, forward-looking statements are subject to numerous assumptions and risk factors including those discussed in our Annual Information Form and most recent MD&A which are incorporated herein by reference and are available through SEDAR at www.sedar.com. The forward-looking statements contained in this news release are expressly qualified by this cautionary statement and are made as of the date hereof. The Company disclaims any intention and has no obligation or responsibility, except as required by law, to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

SOURCE Resverlogix Corp.


Back to News